ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
UK to expand NHS Subscription Pilot! Consultation Period launches
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
FDA analysis of 40-years of antibacterial development: Dheman et al.
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
FDA: Early endpoints and late endpoints suggest a path to global regulatory convergence (Bart et al.)
De-risking vaccine development: Insights spanning decades of experience
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
Modeling the value of an effective antibiotic — Megiddo et al.
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
What does an antibiotic cost to develop? What is it worth? How to afford it?
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet