ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
NIAID workshop: What is a robust PK-PD package?
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
Draft EMA antibacterial guidance: Analysis
Lancet: 10-20-30 targets to address AMR by 2030
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Developing systemic & inhaled antibiotics for lung infections
Modeling the value of an effective antibiotic — Megiddo et al.
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
Melinta goes bankrupt / Never let a good crisis go to waste
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet